BDBM617459 US20230285377, Example 43

SMILES COCc1cc(ccn1)-c1nsc(n1)[C@@H](C)NC(=O)c1cc(nn1C)C(F)(F)F

InChI Key InChIKey=WZTRFCISNUKQHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617459   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617459(US20230285377, Example 43)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent