BDBM618705 (1S,2S,4R,8S,9S,11S,12R,13S,19S)-8-{2-[4-Amino(2,3,5,6-2H4)phenoxy]acetyl}-12,19-difluoro-11-hydroxy-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one::US11760775, Compound 6-ID

SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)COc1ccc(N)cc1

InChI Key InChIKey=GRHPPGYNDIZMRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 618705   

TargetGlucocorticoid receptor(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM618705((1S,2S,4R,8S,9S,11S,12R,13S,19S)-8-{2-[4-Amino(2,3...)
Affinity DataIC50: 10nMAssay Description:To evaluate the ability of novel steroids to bind to the Glucocorticoid Receptor (GR), a cell-free binding assay was performed using a LanthaScreen T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
Go to US Patent