BDBM618706 US11760775, Compound 6-II

SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)COc1ccc(N)c(OC)c1

InChI Key InChIKey=GAVKVPFNIBEJIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 618706   

TargetGlucocorticoid receptor(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM618706(US11760775, Compound 6-II)
Affinity DataIC50: 10nMAssay Description:To evaluate the ability of novel steroids to bind to the Glucocorticoid Receptor (GR), a cell-free binding assay was performed using a LanthaScreen T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
Go to US Patent