BDBM61908 2-methyl-1,2-benzothiazol-3-one::KUC103657N::acs.jmedchem.1c00409_ST.167::cid_351236

SMILES Cn1sc2ccccc2c1=O

InChI Key InChIKey=RDWXSJCICPOOKO-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 61908   

TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 2.50E+4nMAssay Description:Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African slee...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetProbable global transcription activator SNF2L2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataEC50:  9.12E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 780nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed