BDBM619564 (Z)-2-(((2-butyl-7-fluorobenzo[d]thiazol-6-yl)oxy)methyl)-3-fluoroprop-2-en-1-amine 4-methylbenzenesulfonate::US11787791, Example 15::US20230295140, Example 15

SMILES CCCCc1nc2ccc(OC\C(CN)=C/F)c(F)c2s1

InChI Key InChIKey=BDHYDROATRLMBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 619564   

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619564(US20230295140, Example 15 | US11787791, Example 15...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619564(US20230295140, Example 15 | US11787791, Example 15...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619564(US20230295140, Example 15 | US11787791, Example 15...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619564(US20230295140, Example 15 | US11787791, Example 15...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent