BDBM619585 (E)-2-(((2-(4,4-dimethylcyclohexyl)benzo[d]oxazol-6-yl)oxy)methyl)-3-fluoroprop-2-en-1-amine 4-methylbenzenesulfonate::US11787791, Example 36::US20230295140, Example 36

SMILES CC1(C)CCC(CC1)c1nc2ccc(OC\C(CN)=C\F)cc2o1

InChI Key InChIKey=KYGPXOOIFPUQLZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 619585   

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 2.00E+4nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 550nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 2.00E+4nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619585(US20230295140, Example 36 | US11787791, Example 36...)
Affinity DataIC50: 550nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent