BDBM6208 Indole deriv. 17::N-(3-Chloro-1H-indol-7-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine::N-(3-chloro-1H-indol-7-yl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine

SMILES COc1cc2c(Nc3cccc4c(Cl)c[nH]c34)ncnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=YJBXXVZEYNUBTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6208   

LigandPNGBDBM6208(N-(3-chloro-1H-indol-7-yl)-6-methoxy-7-[3-(morphol...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2005
Entry Details Article
PubMed
LigandPNGBDBM6208(N-(3-chloro-1H-indol-7-yl)-6-methoxy-7-[3-(morphol...)
Affinity DataIC50: 2.32E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-RRTK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2005
Entry Details Article
PubMed