BDBM621055 6-(1-(6-methylpyridin-2-yl)-1H-pyrazol-5-yl)benzo[d]thiazole ::US20230303562, Example 1

SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ncsc2c1

InChI Key InChIKey=VLLYNPWTZGQZOJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 621055   

TargetActivin receptor type-1(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621055(US20230303562, Example 1 | 6-(1-(6-methylpyridin-2...)
Affinity DataIC50: 48.6nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetTGF-beta receptor type-2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621055(US20230303562, Example 1 | 6-(1-(6-methylpyridin-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental method: According to the instructions of ADP-Glo Kinase Detection Kit (Promega), the inhibitory effect of the compounds of the present i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621055(US20230303562, Example 1 | 6-(1-(6-methylpyridin-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:1. Test System: Kit: Predictor hERG fluorescence polarization detection kit (ThermoFisher), the kit contained the following components: positive cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
Go to US Patent