BDBM621066 US20230303562, Example 4

SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ccnn2c1

InChI Key InChIKey=DEIKIANEDBRPHC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 621066   

TargetActivin receptor type-1(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621066(US20230303562, Example 4)
Affinity DataIC50: 12nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621066(US20230303562, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:1. Test System: Kit: Predictor hERG fluorescence polarization detection kit (ThermoFisher), the kit contained the following components: positive cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetCytochrome P450 1A2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621066(US20230303562, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:3.2. Inhibition of CYP2D6: Test group: The test compound of different concentration was added to the microplate, and Luciferin-ME EGE (3 μM), K3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetCytochrome P450 2D6(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621066(US20230303562, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:3.2. Inhibition of CYP2D6: Test group: The test compound of different concentration was added to the microplate, and Luciferin-ME EGE (3 μM), K3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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TargetCytochrome P450 3A4(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621066(US20230303562, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:3.2. Inhibition of CYP2D6: Test group: The test compound of different concentration was added to the microplate, and Luciferin-ME EGE (3 μM), K3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
Go to US Patent