BDBM625040 US11780852, Example 6-53

SMILES CNCc1cnc2ccc(-c3ccc(F)c(F)c3OCCc3c(C(O)C(C)C)nn(C)c3C)cn12

InChI Key InChIKey=CLRISPXDMGEKRJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625040   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Myricx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 625040BDBM625040(1-{4-[2-(2,3-difluoro-6-{3-[(methylamino)methyl]im...)
Affinity DataIC50: 2nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent