BDBM626566 US11787780, Example 261::US11787780, Example 266::US11787780, Example 296

SMILES Cc1cc2n(ncc2cc1C1(Cc2ccccc2)CCN(C1)S(=O)(=O)c1cnn(C)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=TYEIFYCWPYWRIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 626566   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

US Patent
LigandPNGBDBM626566(US11787780, Example 266 | US11787780, Example 296 ...)
Affinity DataIC50: 2.90nMAssay Description:Binding of test compounds to the glucocorticoid receptor (GR) is determined using a fluorescence polarisation (FP) assay utilising a recombinant liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

US Patent
LigandPNGBDBM626566(US11787780, Example 266 | US11787780, Example 296 ...)
Affinity DataIC50: 4.70nMAssay Description:Binding of test compounds to the glucocorticoid receptor (GR) is determined using a fluorescence polarisation (FP) assay utilising a recombinant liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

US Patent
LigandPNGBDBM626566(US11787780, Example 266 | US11787780, Example 296 ...)
Affinity DataIC50: 6.90nMAssay Description:Binding of test compounds to the glucocorticoid receptor (GR) is determined using a fluorescence polarisation (FP) assay utilising a recombinant liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent