BDBM628780 US20230339890, Compound 84::US20230339890, Compound 88::US20230339890, Compound 89

SMILES Cc1ccncc1C(O)CN(CC1COC1)C(=O)Cc1ccc(nc1)C(F)(F)F

InChI Key InChIKey=ZQLUSVSMAJBRDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 628780   

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628780(US20230339890, Compound 84 | US20230339890, Compou...)
Affinity DataIC50: 1.00E+3nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628780(US20230339890, Compound 84 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628780(US20230339890, Compound 84 | US20230339890, Compou...)
Affinity DataIC50: 1.00E+3nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent