BDBM628785 US20230339890, Compound 35::US20230339890, Compound 36::US20230339890, Compound 97

SMILES CCCN(CC(O)c1cccnn1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ZOODMKUQXCWWFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 628785   

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628785(US20230339890, Compound 35 | US20230339890, Compou...)
Affinity DataIC50: 550nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628785(US20230339890, Compound 35 | US20230339890, Compou...)
Affinity DataIC50: 1.00E+3nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628785(US20230339890, Compound 35 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent