BDBM629228 Synthesis of 4-(4-chloro-1-(4-fluorophenyl)-5-hydroxy-2-(I-methoxy-2-methylpropan-2-yl)-1H-indol-3-yl)benzoic acid (178)::US20230339915, Compound 178

SMILES COCC(C)(C)c1c(-c2ccc(cc2)C(O)=O)c2c(Cl)c(O)ccc2n1-c1ccc(F)cc1

InChI Key InChIKey=YBAWSYHHSPARRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629228   

TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629228(US20230339915, Compound 178 | Synthesis of 4-(4-ch...)
Affinity DataIC50: 2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
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Date in BDB:
12/10/2023
Entry Details
US Patent