BDBM631222 (4aR,8aS)-6-(4-((2-chloro-4-fluorophenoxy)methyl)-4-methylpiperidine-1-carbonyl)hexahydro-2H-pyrido[4,3-b][1,4]oxazin-3(4H)-one::US11802133, Example 79

SMILES CC1(COc2ccc(F)cc2Cl)CCN(CC1)C(=O)N1CC[C@@H]2OCC(=O)N[C@@H]2C1

InChI Key InChIKey=VHWHJSDFNPEZPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631222   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631222(US11802133, Example 79 | (4aR,8aS)-6-(4-((2-chloro...)
Affinity DataIC50: 1nMAssay Description:The 4-NPA assay was carried out in 384 well assay plates (black with clear bottom, non-binding surface treated, Corning Ref. 3655) in a total volume ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent