BDBM63226 US12577235, Compound 1

SMILES O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O)N[C@@H]1CCCc2cc(C(F)(F)F)oc21

InChI Key InChIKey=JMULEYOMVPJOPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63226   

TargetC-X-C chemokine receptor type 2(Human)
Shenzhen Optimum Biological Technology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 63226BDBM63226(US12577235, Compound 1)
Affinity DataIC50: 22nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2026
Entry Details
US Patent