BDBM632550 (2R,3R,4S,5R,6R)-N-(3,5-dichlorophenyl)-4-(4-(3,5-difluoro-4-methylphenyl)- 1H-1,2,3-triazol-1-yl)-3,5-dihydroxy-N-((1S,2S)-2-hydroxycyclopentyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-2-carboxamide::US20230348442, Example 1H.4.2

SMILES Cc1c(F)cc(cc1F)-c1cn(nn1)[C@H]1[C@@H](O)[C@@H](CO)O[C@H]([C@@H]1O)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=FIWZXEHJUISPKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 632550   

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM632550(US20230348442, Example 1H.4.2 | (2R,3R,4S,5R,6R)-N...)
Affinity DataIC50: 3.56E+3nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM632550(US20230348442, Example 1H.4.2 | (2R,3R,4S,5R,6R)-N...)
Affinity DataIC50: 22.7nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent