BDBM634071 2-[4-({(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl}amino)-2,7-dimethylpyrido[2,3-d]pyrimidin-6-yl]-1 lambda6,2-thiazolidine-1,1-dione::US20230357239, Example 39

SMILES C[C@@H](Nc1nc(C)nc2nc(C)c(cc12)N1CCCS1(=O)=O)c1cccc(C(F)F)c1F

InChI Key InChIKey=RCVVYPLTBLXFQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634071   

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
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US Patent
LigandPNGBDBM634071(US20230357239, Example 39 | 2-[4-({(1R)-1-[3-(difl...)
Affinity DataIC50: 16.2nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
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