BDBM634117 US20230357248, Example 8

SMILES OCCO[C@@H]1C[C@@H](CO)OC[C@@H]1Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12

InChI Key InChIKey=KIQFPWISJSFZMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634117   

TargetTyrosine-protein kinase BTK [C481S](Human)
Medshine Discovery

US Patent
LigandPNGBDBM634117(US20230357248, Example 8)
Affinity DataIC50: 8.90nMAssay Description:The specific assay process of BTK enzyme activity assay is as follows: Buffer: 20 mM 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (Hepes) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
Go to US Patent