BDBM635770 US20230365488, Compound 2a

SMILES COc1ccccc1[C@H]1[C@@H]([C@@H]([C@@H]1C(=O)Oc1cccc(c1)-c1ccc2OCOc2c1)c1ccccc1OC)C(O)=O

InChI Key InChIKey=HECOJMYJBUNGJH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 635770   

TargetFatty acid-binding protein 5(Human)
The State University of New York

US Patent
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  890nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetFatty acid-binding protein 5(Human)
The State University of New York

US Patent
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  890nMAssay Description:Displacement of fluorescent probe DAUDA from FABP5 (unknown origin) assessed as inhibition constant by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetFatty acid-binding protein, brain(Human)
The State University of New York

US Patent
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  1.86E+3nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetFatty acid-binding protein, brain(Human)
The State University of New York

US Patent
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  1.86E+3nMAssay Description:Displacement of fluorescent probe ANS from FABP7 (unknown origin) assessed as inhibition constant by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetFABP3 protein(Human)
The State University of New York

US Patent
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  8.00E+3nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetFatty acid-binding protein, heart(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM635770(US20230365488, Compound 2a)
Affinity DataKi:  8.00E+3nMAssay Description:Displacement of fluorescent probe DAUDA from FABP3 (unknown origin) assessed as inhibition constant by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed