BDBM6366 5-methyl-2-{[4-(piperazin-1-yl)phenyl]amino}-8-(propan-2-yl)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::8-Isopropyl-5-methyl-2-(4-piperazin-1-yl-phenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido[2,3-d]pyrimidin-7-one 13

SMILES CC(C)n1c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c(C)cc1=O

InChI Key InChIKey=MCTQZILVMGKIKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6366   

LigandPNGBDBM6366(5-methyl-2-{[4-(piperazin-1-yl)phenyl]amino}-8-(pr...)
Affinity DataIC50: 265nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6366(5-methyl-2-{[4-(piperazin-1-yl)phenyl]amino}-8-(pr...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6366(5-methyl-2-{[4-(piperazin-1-yl)phenyl]amino}-8-(pr...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6366(5-methyl-2-{[4-(piperazin-1-yl)phenyl]amino}-8-(pr...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed