BDBM636730 E)-4-(3-(4-(6-(4-(2-(4-chloro-2-fluorophenyl)-1-(1H-indazol-5-yl)but-1-enyl)phenoxy)hexyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one ::US11826430, Compound 2.52
SMILES CC\C(=C(\c1ccc(OCCCCCCN2CCN(CC2)C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)cc1)c1ccc2[nH]ncc2c1)c1ccc(Cl)cc1F
InChI Key InChIKey=VIJNLQXJSHLTCN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 636730
Affinity DataIC50: 187nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:ERα binding was assessed by the LanthaScreen TR-FRET ER Alpha Competitive Binding Assay at Thermo Fisher. In this assay, a terbium-labeled anti-...More data for this Ligand-Target Pair