BDBM637 (2R,4S)-2-[(R)-(benzylcarbamoyl)(1-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide::[2R-[2a(R*),4B]]-4-Carbamoyl-5,5-dimethyl-a-[(phenylacetyl)amino]-N-(phenylmethyl)-2-thiazolidineacetamide::penicillin deriv. 50

SMILES [H][C@]1(N[C@@H](C(N)=O)C(C)(C)S1)[C@H](NC(=O)Cc1ccccc1)C(=O)NCc1ccccc1

InChI Key InChIKey=FHJRDQOWYRRIAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandPNGBDBM637([2R-[2a(R*),4B]]-4-Carbamoyl-5,5-dimethyl-a-[(phen...)
Affinity DataIC50: 2.30E+5nMpH: 6.0 T: 2°CAssay Description:IC50 values were obtained by assaying the enzyme against the synthetic substrate peptide KQGTVSFNFPQIT, which was tritiated at the proline residue, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2004
Entry Details Article
PubMed