BDBM639299 5-fluoro-N-(trans-4-(hydroxymethyl)cyclohexyl)-7-(2-(2,2,2-trifluoroethoxy)phenyl) benzofuran-2-carboxamide::US20230391758, Compound 1

SMILES Cc1cc(-c2ccccc2OCC(F)(F)F)c2oc(cc2c1)C(=O)CC1CC[C@H](CO)CC1

InChI Key InChIKey=VYNRYNLZLDHYGD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639299   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639299(5-fluoro-N-(trans-4-(hydroxymethyl)cyclohexyl)-7-(...)
Affinity DataEC50:  0.990nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent