BDBM639304 7-[5-chloro-2- (difluoromethoxy)-3-pyridyl]- N-(4-hydroxynorbornan-1- yl)benzofuran-2-carboxamide::US20230391758, Compound 6

SMILES OC12CCC(CC1)(C2)NC(=O)c1cc2cccc(-c3cc(Cl)cnc3OC(F)F)c2o1

InChI Key InChIKey=YXDIWECCSHZDOR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639304   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639304(7-[5-chloro-2- (difluoromethoxy)-3-pyridyl]- N-(4-...)
Affinity DataEC50:  0.870nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent