BDBM639307 (R and S)-N-[3-(2-hydroxy-1- methyl-ethyl)-1- bicyclo[1.1.1]pentanyl]-7-[2- (2,2,2- trifluoroethoxy)phenyl] benzofuran-2-carboxamide::US20230391758, Compound 9

SMILES CC(CO)C12CC(C1)(C2)NC(=O)c1cc2cccc(-c3ccccc3OCC(F)(F)F)c2o1

InChI Key InChIKey=CNEBHHNPWQSEET-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639307   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639307((R and S)-N-[3-(2-hydroxy-1- methyl-ethyl)-1- bicy...)
Affinity DataEC50:  1.70nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
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