BDBM639328 7-(2,3-difluoro-6-methoxy- phenyl)-N-[(1R,3S)-3- hydroxycyclopentyl] benzofuran-2-carboxamide::US20230391758, Compound 30

SMILES COc1ccc(F)c(F)c1-c1cccc2cc(oc12)C(=O)N[C@@H]1CC[C@H](O)C1

InChI Key InChIKey=UYGQHNCYAYFEJL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639328   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639328(7-(2,3-difluoro-6-methoxy- phenyl)-N-[(1R,3S)-3- h...)
Affinity DataEC50:  3.40nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent