BDBM640087 2-Cyclobutoxy-4-{6-[2-(6-methoxy-4-methyl-benzofuran-5-yl)-ethylamino]-pyrimidin- 4-yl}-benzoic acid::US11839613, Example 208

SMILES COc1cc2occc2c(C)c1CCNc1cc(ncn1)-c1ccc(C(O)=O)c(OC2CCC2)c1

InChI Key InChIKey=LLSZBAJHHYLNRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640087   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640087(2-Cyclobutoxy-4-{6-[2-(6-methoxy-4-methyl-benzofur...)
Affinity DataIC50: 5nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640087(2-Cyclobutoxy-4-{6-[2-(6-methoxy-4-methyl-benzofur...)
Affinity DataIC50: 248nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent