BDBM640341 8-Amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(dimethylamino)-2-oxoethyl)- 1H-pyrazole-4-yl)phenyl)-1,7- naphthyridine-3-carboxamide::US11840531, Compound 3.43

SMILES CN(C)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ncc(cc12)C(=O)NCC1CC1

InChI Key InChIKey=GDEQWRWKDYKBRI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640341   

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640341(8-Amino-N-(cyclopropylmethyl)-5-(4- (1-(2-(dimethy...)
Affinity DataIC50: 0.880nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
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