BDBM640387 US11840523, LBC-00004 06

SMILES CCc1cc(cc2cnc(N[C@H]3CC[C@H](N)CC3)nc12)-c1ccc(NS(=O)(=O)CCC(F)(F)F)nc1OC

InChI Key InChIKey=IBEXKKOMCWOTQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640387   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University of California

US Patent
LigandPNGBDBM640387(US11840523, LBC-00004 06)
Affinity DataIC50: 7.40nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent