BDBM640691 US20230399319, Example 2-247

SMILES CCCCS(=O)(=O)N1CCN(CC1)S(=O)(=O)NC(=O)c1coc(Nc2cc(ccc2C)C(F)(F)F)n1

InChI Key InChIKey=NCNMAOKEICMLBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640691   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM640691(US20230399319, Example 2-247)
Affinity DataIC50: 22nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent