BDBM642515 5-Isopropoxy-N-(1- (methylsulfonyl)piperidin- 4-yl)-6-(1H-pyrazol- 4-yl)- [1,2,4]triazolo[1,5- a]pyrazin-2-amine::US11851426, Example 141::US11851426, Example 142

SMILES CC(C)Oc1c(ncc2nc(NC3CCN(CC3)S(C)(=O)=O)nn12)-c1cn[nH]c1

InChI Key InChIKey=RWLKEQNUAUSCJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 642515   

LigandPNGBDBM642515(US11851426, Example 142 | 5-Isopropoxy-N-(1- (meth...)
Affinity DataIC50: 20nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2024
Entry Details
US Patent

LigandPNGBDBM642515(US11851426, Example 142 | 5-Isopropoxy-N-(1- (meth...)
Affinity DataIC50: 20nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2024
Entry Details
US Patent