BDBM644057 US11866429, Compound 1.027::US11866429, Compound 1.028

SMILES COc1nc(ccc1CNC[C@H](O)CO)-c1cccc(c1Cl)-c1cccc(Nc2nc(C)nc3cccnc23)c1C

InChI Key InChIKey=UJPVFZZWSMAWOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644057   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM644057(US11866429, Compound 1.028 | US11866429, Compound ...)
Affinity DataIC50: 10nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM644057(US11866429, Compound 1.028 | US11866429, Compound ...)
Affinity DataIC50: 10nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent