BDBM644108 US11866429, Compound 1.076

SMILES COc1nc(ccc1CN1CC(C1)C(O)=O)-c1cccc(c1Cl)-c1cccc(Nc2nccc3nccnc23)c1C

InChI Key InChIKey=YTBKRKXUZJHCTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 644108   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM644108(US11866429, Compound 1.076)
Affinity DataIC50: 10nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent