BDBM644265 6-chloro-4-(4-((4-fluoro-2-hydroxyphenyl)(4-fluorophenyl)methyl)piperazin-1-yl)-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carbonitrile::US11866430, Example 222

SMILES Cn1c2ccc(Cl)nc2c(N2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2O)c(C#N)c1=O

InChI Key InChIKey=LLMZNDLSZORGQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 644265   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644265(US11866430, Example 222 | 6-chloro-4-(4-((4-fluoro...)
Affinity DataIC50: 83nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2024
Entry Details
US Patent