BDBM645392 US20240016810, Compound TABLE 16.5::US20240208964, Biochemistry 5

SMILES C1CN(CCO1)c1cc(nc2cc(nn12)-c1ccncc1)-c1cccc(n1)-c1ccccc1

InChI Key InChIKey=LYPMTYMIIFVKSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645392   

LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent