BDBM64544 7-[(1,3-benzothiazol-2-ylamino)-(2-furanyl)methyl]-8-quinolinol::7-[(1,3-benzothiazol-2-ylamino)-(2-furyl)methyl]quinolin-8-ol::7-[(1,3-benzothiazol-2-ylamino)-(furan-2-yl)methyl]quinolin-8-ol::MLS000089236::SMR000060957::cid_2998355

SMILES Oc1c(ccc2cccnc12)C(Nc1nc2ccccc2s1)c1ccco1

InChI Key InChIKey=USTQBQSRAQTWIR-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 64544   

TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataEC50:  4.68E+3nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataEC50:  1.80E+5nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataEC50:  3.34E+4nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataEC50:  1.98E+3nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetRecBCD enzyme subunit RecD(Escherichia coli (strain K12))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64544(SMR000060957 | 7-[(1,3-benzothiazol-2-ylamino)-(2-...)
Affinity DataIC50: 1.19E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay