BDBM645561 US20240018122, Example 177::[6-(5-chloro-2-fluorophenyl)- 4-({7-[2-(4-methylpiperazin- 1-yl)ethoxy]quinolin-4-yl}- amino)pyridazin-3-yl]methanol

SMILES CN1CCN(CCOc2ccc3c(Nc4cc(nnc4CO)-c4cc(Cl)ccc4F)ccnc3c2)CC1

InChI Key InChIKey=GQMVUPIZTCCSJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645561   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645561(US20240018122, Example 177 | [6-(5-chloro-2-fluoro...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645561(US20240018122, Example 177 | [6-(5-chloro-2-fluoro...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent