BDBM645663 (S)-6-chloro-N-(tetrahydrofuran-3- yl)-8-(2-(2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 5

SMILES FC(F)(F)COc1ccccc1-c1cc(Cl)cn2cc(nc12)C(=O)N[C@H]1CCOC1

InChI Key InChIKey=UJSCCCOLXKVUON-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645663   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645663(US20240018140, Compound 5 | (S)-6-chloro-N-(tetrah...)
Affinity DataEC50:  0.910nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent