BDBM645667 (R or S)-N-(1,1,1-trifluoro-3- hydroxy-2-methylpropan-2-yl)-8-(2- (2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 10::US20240018140, Compound 9

SMILES CC(CO)(NC(=O)c1cn2cccc(-c3ccccc3OCC(F)(F)F)c2n1)C(F)(F)F

InChI Key InChIKey=SQHBWROLDILDIS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645667   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645667(US20240018140, Compound 10 | (R or S)-N-(1,1,1-tri...)
Affinity DataEC50:  2.30nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645667(US20240018140, Compound 10 | (R or S)-N-(1,1,1-tri...)
Affinity DataEC50:  7.20nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent