BDBM645681 6-chloro-N-((1S,2R,4S and 1R, 2S,4R)-2-fluoro-4- hydroxycyclohexyl)-8-(2-(2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 22

SMILES O[C@H]1CC[C@H](NC(=O)c2cn3cc(Cl)cc(-c4ccccc4OCC(F)(F)F)c3n2)[C@H](F)C1

InChI Key InChIKey=NZRLPGHGAQOQFA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645681   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645681(US20240018140, Compound 22 | 6-chloro-N-((1S,2R,4S...)
Affinity DataEC50:  0.720nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent