BDBM645685 US20240018140, Compound 26::cis or trans-6-fluoro-N-(4-hydroxy-4- methylcyclohexyl)-8-(2-(2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridine-2-carboxamide

SMILES CC1(O)CCC(CC1)NC(=O)c1cn2cc(F)cc(-c3ccccc3OCC(F)(F)F)c2n1

InChI Key InChIKey=RKMFALNISWLWEW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645685   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645685(US20240018140, Compound 26 | cis or trans-6-fluoro...)
Affinity DataEC50:  0.790nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent