BDBM645689 8-(5-chloro-2-methoxyphenyl)-N-(4- hydroxybicyclo[2.2.1]heptan-1- yl)imidazo[1,2-a]pyridine-2- carboxamide::US20240018140, Compound 30

SMILES COc1ccc(Cl)cc1-c1cccn2cc(nc12)C(=O)NC12CCC(O)(CC1)C2

InChI Key InChIKey=QQXDDWKBAKBWHC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645689   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645689(US20240018140, Compound 30 | 8-(5-chloro-2-methoxy...)
Affinity DataEC50:  5.60nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent