BDBM645696 N-(1-hydroxy-2-methylpropan-2-yl)- 8-(2-(2,2,2-trifluoroethoxy)phenyl)-6- (trifluoromethyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 37

SMILES CC(C)(CO)NC(=O)c1cn2cc(cc(-c3ccccc3OCC(F)(F)F)c2n1)C(F)(F)F

InChI Key InChIKey=XUGJXDSTIMSLEC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645696   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645696(US20240018140, Compound 37 | N-(1-hydroxy-2-methyl...)
Affinity DataEC50:  4.5nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent