BDBM645701 (S)-N-(tetrahydro-2H-pyran-3-yl)-8-(2-(2,2,2- trifluoroethoxy)phenyl)-6- (trifluoromethyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 42

SMILES FC(F)(F)COc1ccccc1-c1cc(cn2cc(nc12)C(=O)N[C@H]1CCCOC1)C(F)(F)F

InChI Key InChIKey=LDEGTMJUXHJUPI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645701   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645701(US20240018140, Compound 42 | (S)-N-(tetrahydro-2H-...)
Affinity DataEC50:  2.5nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent