BDBM645813 Step 1: ethyl N-benzyl-N-propionylglycinate::US20240018157, Example 15

SMILES C[C@@]1(CN(C(=O)Nc2cnc(c(Cl)c2)-n2nccn2)c2cnc3cc(Cl)nn3c12)C(F)(F)F

InChI Key InChIKey=LWFJAKMDGYYQHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645813   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645813BDBM645813(US20240018157, Example 15 | Step 1: ethyl N-benzyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full length His-tagged MALT1 (1 to 824 residues) infected in baculovirus infected Insect cells using Ac-LRSR-AMC as substrate inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645813BDBM645813(US20240018157, Example 15 | Step 1: ethyl N-benzyl...)
Affinity DataIC50: 55nMAssay Description:The final assay buffer includes 2 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent