BDBM645949 US20240018157, Example 151

SMILES CN(C1CC1)C(=O)c1ncc(NC(=O)N2C[C@](C)(c3c2cnc2cc(Cl)nn32)C(F)(F)F)cc1C(F)F

InChI Key InChIKey=STFWHUHUEWSXKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645949   

LigandPNGBDBM645949(US20240018157, Example 151)
Affinity DataIC50: 10nMAssay Description:The final assay buffer includes 1 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent