BDBM645950 Step 1: 3-chloro-5-isocyanato-2-(2H-1,2,3-triazol-2-yl)pyridine::US20240018157, Example 152

SMILES Cc1cn2ncc3N(C[C@](C)(c3c2n1)C(F)(F)F)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1

InChI Key InChIKey=LIWIBERCTKEQGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645950   

LigandPNGBDBM645950(US20240018157, Example 152 | Step 1: 3-chloro-5-is...)
Affinity DataIC50: 10nMAssay Description:The final assay buffer includes 1 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent