BDBM647623 US20240025900, Example 1::US20240025900, Example 2

SMILES CN1c2c(N3CCN(CC3CC1=O)C(c1ccc(F)cc1)c1ccc(F)cc1)c1nc(ccc1n(C)c2=O)C#N

InChI Key InChIKey=HJTJHILJTXSFDR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 647623   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM647623(US20240025900, Example 2 | US20240025900, Example ...)
Affinity DataIC50: 40nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM647623(US20240025900, Example 2 | US20240025900, Example ...)
Affinity DataIC50: 1.10E+3nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM647623(US20240025900, Example 2 | US20240025900, Example ...)
Affinity DataIC50: 120nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM647623(US20240025900, Example 2 | US20240025900, Example ...)
Affinity DataIC50: 40nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent