BDBM647626 US20240025900, Example 4

SMILES Cn1c2ccc(CC#N)nc2c2N3CCN(C[C@@H]3COC(=O)c2c1=O)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=NFSZGXFQZIORHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 647626   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM647626(US20240025900, Example 4)
Affinity DataIC50: 40nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM647626(US20240025900, Example 4)
Affinity DataIC50: 40nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent